This treatment is offered to woman that do not ovulate or have irregular periods. The commonest reason for not ovulating is Polycystic ovarian syndrome (PCOS). Women with PCOS tend to skip their periods and may have skin problems like an oily skin, acne and increase in facial and body hair. The other reasons for not ovulating are the contraceptive injection, thyroid abnormalities, high prolactin levels, strenuous physical exercise and excessive weight gain and weight loss.
The commonest medication given to induced ovulation is Clomid / Fertomid (Clomiphene Citrate). Some woman with polycystic ovarian syndrome may be resistant to ovulation induction with Clomid. Letrozole tablets or fertility injections (e.g.) Gonal F / Menopur are given in such cases.
The aim of ovulation induction is to produce 1 to 2 mature follicles (eggs).
The medication is started on the 2nd or 3rd day of the period. It is taken for 5 days. For woman that do not get periods, they will be given Provera or Duphaston or the oral contraceptive pill to induce a period.
The response of the ovary is monitored by transvaginal ultrasound. The first ultrasound is done on cycle day 12-14. The size of a mature follicle is 18-20 mm. If the follicle is not mature, a repeat ultrasound will be done a few days later. A mature follicle indicates the fertile part of the cycle.
Ovulation is confirmed by doing a blood tests for progesterone 7 days later.